Improved Detection of Tuberculosis and Multidrug-Resistant Tuberculosis among Tibetan Refugees, India

Dierberg, K. L. and Dorjee, K. and Salvo, F. and Cronin, W. A. and Boddy, J. and Cirillo, D. and Sadutshang, T. and Chaisson, R. E. (2016) Improved Detection of Tuberculosis and Multidrug-Resistant Tuberculosis among Tibetan Refugees, India Emerg Infect Dis, 22 (3). pp. 463-468.

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Official URL: https://dx.doi.org/10.3201/eid2203.140732

Abstract

The incidence of tuberculosis (TB) among Tibetan refugees in India is 431 cases/100,000 persons, compared with 181 cases/100,000 persons overall in India in 2010. More than half of TB cases in these refugees occur among students, monks, and nuns in congregate settings. We sought to increase TB case detection rates for this population through active case finding and rapid molecular diagnostics. We screened 27,714 persons for symptoms of TB and tested 3,830 symptomatic persons by using an algorithm incorporating chest radiography, sputum smear microscopy, culture, and a rapid diagnostic test; 96 (2.5%) cases of TB were detected (prevalence 346 cases/100,000 persons). Of these cases, 5% were multidrug-resistant TB. Use of the rapid diagnostic test and active case finding enabled rapid detection of undiagnosed TB cases in congregate living settings, which would not have otherwise been identified. The burden of TB in the Tibetan exile population in India is extremely high and requires urgent attention.

Item Type: Article
Uncontrolled Keywords: ACF; Tuberculosis; Multidrug-Resistant Tuberculosis; Tibetan Refugees; India
Subjects: Tuberculosis > Case Finding
Tuberculosis > Epidemiology
Institutions: National Task Force, Zonal Task Force & State Task Force of Medical Colleges
Depositing User: Mr SANJAY SINGH
Date Deposited: 02 Nov 2017 20:59
Last Modified: 02 Nov 2017 20:59
URI: http://tbresearch.ntiindia.org.in/id/eprint/2338

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