Non-response to the intensive phase of anti-tuberculosis treatment in children: evaluation and outcome

Yadav, A. and Sethi, G. R. and Mantan, M. and Dhingra, D. (2014) Non-response to the intensive phase of anti-tuberculosis treatment in children: evaluation and outcome Int J Tuberc Lung Dis, 18 (4). pp. 394-396.

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Abstract

The present study evaluates the causes for the persistence of symptoms and radiological signs after at least 2 months of intensive anti-tuberculosis treatment in children. In this prospective observational study, 26 paediatric patients with partial or no response to anti-tuberculosis treatment after the 2-month intensive phase were enrolled. After a detailed history and workup, it was found that 9 (34.6%) patients had a wrong initial diagnosis, while 12 (46.2%) had either received inadequate treatment or had complications requiring prolonged treatment; 5 (19.2%) failed to respond. Failure to respond to anti-tuberculosis treatment in paediatric tuberculosis seems to be over-diagnosed.

Item Type: Article
Uncontrolled Keywords: Failure to respond; Resistant tuberculosis; Irrational anti-tuberculosis treatment
Subjects: Tuberculosis > Pediatric TB
Institutions: Zonal Task Force-State Task Force
Depositing User: Mr SANJAY SINGH
Date Deposited: 03 Apr 2014 06:48
Last Modified: 03 Apr 2014 06:48
URI: http://tbresearch.ntiindia.org.in/id/eprint/1854

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